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Nicole Wa

Member Since 30 Oct 2012
Offline Last Active Dec 21 2012 01:54 AM
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Posts I've Made

In Topic: How long is the suppressive efficiency by siRNA or shRNA

02 November 2012 - 08:45 PM

View Postpcrman, on 02 November 2012 - 08:45 AM, said:

siRNA transfection has transient knockdown lasting for 5-7 days. Stable expression of shRNA should give persistent knockdown as long as the shRNA is expressed.

if the shRNA integrates into genome, then should be stable knockdown. But if not, whether the shRNA effect will be similar as siRNA to be temporary (few days) ? or the temporary knockdown of shRNA can also retain longer than siRNA?

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