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net123

Member Since 31 Dec 2010
Offline Last Active Jul 24 2012 12:17 AM

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Liver S9 Microsomes with NADPH and Glucose 6 Phosphate

24 July 2012 - 12:17 AM

Hi, so I am looking at protocol for metabolizing drugs using liver microsomes. I am just wondering what the need for NADPH and glucose 6 phosphate reagents are. I understand that NADPH is necessary for the oxidation of the the substance but what use does glucose 6 phosphate have?

Thanks.