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Hi, this is just a general question for toxicologists but I was just wondering how one goes about selecting which species to perform testing on for any toxicity endpoints (developmental/reproductive effects, chronic toxicity, sensitization, etc.).
Why would someone select a mice over a rat (what are the big differences between the two)? And why pick a specific strain of mice (eg. CD-1 mice vs BALB/c mice).
Anyways, if anyone has any good discussion on this material that would be great.
Thanks.
