wizzkid

ANyone know a good chemical/enzyme to use to dephosphorylate serines?  I have used SAP treatment before to dephosphorylate tyrosines....is it efficient for serines too?

appreciate the help guys!

Hi everyone.

I recently managed to find the courage to tell my supervisor that I wished to leave research and leave with a Masters. I admitt I knew early on that I probably would not have stayed and finished my PhD. Now I would like to express that I had always loved science and enjoyed my somewhat limited research experience as an undergrad. However the lab I picked to do my PhD has quite, lets say, a difficult, a tense environment (and not just related to scientific work...people here are difficult over everything). My supervisor shows wanting interest now and again and the project I signed on for from day one was nothing close to what I subsequently did (which i know happens but i feel slightly misled).
After trying to be positive for over a yr and half I decided that it was time to change.
However my supervisor is being quite aggressive towards me when I approach him with the subject. He avoids me in the lab and when he does discuss it with me he persists on using the words "failure", "drop out" and "ruined future career" and "bad on your CV".  This is quite upsetting for me as If I could continue with the PhD I would but I feel that the masters route is the right option for me as present. My big question is: Is leaving with a research masters that digraceful??
My future plan is to undertake a career as an occupational therapist or prehaps medical degree. Is a masters a really bad stain on a CV? And how do I handle my clearly unhappy supervisor.

thanks
Jim