4 replies to this topic

[Animaniac]

Hi there,

Just wondering if anyone has experienced any adverse effects in their rats when given doxycycline either orally or via subcutaneous injection. Any information you may provide would be helpful, such as dose rates, method of dosing, signs presented by the rats or if any deaths occured.

Many thanks

[cellcounter]

Animaniac, on Aug 5 2009, 03:41 PM, said:

Hi there,

Just wondering if anyone has experienced any adverse effects in their rats when given doxycycline either orally or via subcutaneous injection. Any information you may provide would be helpful, such as dose rates, method of dosing, signs presented by the rats or if any deaths occured.

Many thanks

No experience here. But the fourth resultpaper discusses dosing and rate in rat, and what they did to disprove toxicity effects. No mention of adverse effects in rats, I think.

[forinternet12]

Doxycycline? isn't that a medicine given to those who are infected of a Sexually transmitted disease?

partnership administration advice

[vetticus3]

There is a slight problem with the mice/rats becoming dehydrated.  
I used to give it to mice in their drinking water (with sugar).. but the best option, I found (and it's in a couple of papers) is to have the dox in their food.  
the problem is that you can't control the exact amount they have each day... but they don't usually overeat the stuff.

forinternet12:  yup, same medicine.  it's also used to treat acne.  it's also used for malaria.  it's also used to activate siRNA in some vectors.

V

[Animaniac]

forinternet12, on Sep 9 2009, 05:03 PM, said:

Doxycycline? isn't that a medicine given to those who are infected of a Sexually transmitted disease?

partnership administration advice

Doxycycline is a tetracycline antibiotic that is used extensively as a preventative for malaria when travelling into malaria risk areas. Other uses include acne, syphilis and sinusitis