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Methanol toxicity in cell culture


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#16 jakatta70

jakatta70

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Posted 09 September 2009 - 12:38 AM

Good luck, sounds like it should work. I like your 'try it out and see' attitude. Are we allowed to know a bit more detail about your compounds?


Hi,

Im bound by a confidentiality agreement but I can say that they are extremely polar compounds with high molecular weights.

One of my supervisors (I have three unfortunately and two arent even biologists. They are chemists that havent a clue about the assays Im doing!) sent me a graph that a previous student had done with on drug in question. He had told me the drug reduces MMP-9 in vitro. I havent seen that and my n number is 3 while the other previous student only tried this assay once. Well, I get the graph yesterday and there is no MMP-9 reduction over a range of drug concentrations! lol! Maybe I should advise the supervisor to have his eyes (and head) examined!

Edited by jakatta70, 09 September 2009 - 12:39 AM.





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