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Prediciton of antigenic peptides


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#1 PhD

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Posted 02 June 2009 - 07:27 AM

Hello!


I will be raising antibodies against a couple of short peptides and since it costs so much I was wondering whether anyone knew of a database tool that maybe predicts how antigenic a sequence may be? Or maybe optimal peptide sequences for certain proteins?

I will be working with Xenopus in case its useful to know!


Thank you!

#2 brami

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Posted 02 June 2009 - 11:49 PM

Hello PhD

We provide excellent, rapid and reliable services for 'rational design of epitopes'. We guarantee to provide the cheapest service and will beat anybody's price by atleast 20%.

Epitope design and antigenicity prediction is not a simple thing and many factors go into its design.

If you are interested in designing antigenic peptides rationally, then please get in touch with me offline (bhadreshrami@yahoo.com).

best wishes
Rami

#3 SenorManolito

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Posted 15 June 2009 - 06:20 AM

Hi PhD!
Check the following programs (google them! and get familiar with the backgroud too):

Bepipred (http://www.cbs.dtu.d...vices/BepiPred/ )
Bcepred (http://www.imtech.re...pred/index.html )
COBEpro - Scratch (scratch.proteomics.ics.uci.edu).

The best match between a prediction of antigenic stretches of a 1000 aa protein and the real reactivity of an antiserum against fragments of said protein Ive got with Scratch. Try it!

bye SenMan

#4 PhD

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Posted 16 June 2009 - 03:37 AM

thanks!! :)

#5 cellcounter

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Posted 19 June 2009 - 12:52 PM

thanks!! ;)


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