Jump to content

  • Log in with Facebook Log in with Twitter Log in with Windows Live Log In with Google      Sign In   
  • Create Account

Submit your paper to J Biol Methods today!
Photo
- - - - -

Bare morpholino dosing regimens compared in mdx mice


  • Please log in to reply
No replies to this topic

#1 Jon Moulton

Jon Moulton

    Veteran

  • Active Members
  • PipPipPipPipPipPipPipPipPipPip
  • 137 posts
3
Neutral

Posted 28 May 2009 - 10:41 AM

Splice modifying oligos: repeated small doses of unmodified Morpholinos are found to increase dystrophin expression more effectively than single large doses when administered to mdx mice.

Malerba A, Thorogood FC, Dickson G, Graham IR. Dosing regimen has a significant impact on the efficiency of morpholino oligomer-induced exon skipping in mdx mice. Hum Gene Ther. 2009 May 26. [Epub ahead of print]
Jon D. Moulton
Gene Tools, LLC
www.gene-tools.com




Home - About - Terms of Service - Privacy - Contact Us

©1999-2013 Protocol Online, All rights reserved.