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Complement dependent Cytotoxicity


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#1 Doki

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Posted 25 May 2009 - 07:21 PM

What is the difference between Antibody-dependent Complement-mediated Cytotoxicity and Complement-dependent Cytotoxicity?

Making my question clearer : When we say CDC. does it mean both classical and alternative pathway or conventioanlly it only refers to classical pathway only? I suppose Ab-dependent complement mediated cytotoxicity refres to only classical pathway. Or, can they be used interchangeably?

Edited by Nabi, 25 May 2009 - 07:28 PM.

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#2 hugok

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Posted 27 August 2009 - 04:00 AM

View PostNabi, on May 25 2009, 08:21 PM, said:

What is the difference between Antibody-dependent Complement-mediated Cytotoxicity and Complement-dependent Cytotoxicity?

Making my question clearer : When we say CDC. does it mean both classical and alternative pathway or conventioanlly it only refers to classical pathway only? I suppose Ab-dependent complement mediated cytotoxicity refres to only classical pathway. Or, can they be used interchangeably?

I believe both terms, ab-dependent CDC and CDC refer to the same phenomena.
And it refers only to the classical pathway (ab activated pathway)




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