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Neuronal cell culture - why use neonatal brains?


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#1 little friend

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Posted 12 May 2009 - 08:44 AM

Hi, I have been using neonatal rat brains (postnatal day 6-8) for organotypic slice culture of the hypothalamus. I know that neonatal neurons are more versatile and plastic and so they survive culture conditions better. However, I am looking for a reference on exactly why neonatal rats were used for culture and I couldn't find anything. Does anyone know any specific properties of neonatal neurons that make them survive better? Any help would be appreciated! Thanks.

#2 bob1

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Posted 12 May 2009 - 05:53 PM

adult brain cells don't do what, that foetal brain cells do...

key characteristic of development....


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Edited by bob1, 12 May 2009 - 05:53 PM.





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