1 reply to this topic

[SF_HK]

Hi,

I'm would like to know what kind of amino acid mutations to the following RAC1 constitutively active and dominant negative mutants have:

1) RAC1 V12: constitutively active
2) RAC1 17N: dominat negative

All websites just describe theri function and not what aa change?

[WHR]

SF_HK, on Mar 8 2009, 07:45 PM, said:

Hi,

I'm would like to know what kind of amino acid mutations to the following RAC1 constitutively active and dominant negative mutants have:

1) RAC1 V12: constitutively active
2) RAC1 17N: dominat negative

All websites just describe theri function and not what aa change?

Doesn't it mean that the 12th or 17th aa is mutated to V or N?