Dear all:
Hi, we have found a protein that may involve in secretory pathways. By more than one experiments, we see that this protein shows a non-autonomous effect.
However, its sequence does not have a signal peptide.
The only possible hint is that this protien is in a complex and one of its interaction partner has a signal peptide.
Is it possible if this protein can be secreted together with its partner?
And how this is possible?
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Posted 03 March 2009 - 08:52 PM
johnny.jeng03, on Mar 2 2009, 11:41 PM, said:
Dear all:
Hi, we have found a protein that may involve in secretory pathways. By more than one experiments, we see that this protein shows a non-autonomous effect.
However, its sequence does not have a signal peptide.
The only possible hint is that this protien is in a complex and one of its interaction partner has a signal peptide.
Is it possible if this protein can be secreted together with its partner?
And how this is possible?
Hi, we have found a protein that may involve in secretory pathways. By more than one experiments, we see that this protein shows a non-autonomous effect.
However, its sequence does not have a signal peptide.
The only possible hint is that this protien is in a complex and one of its interaction partner has a signal peptide.
Is it possible if this protein can be secreted together with its partner?
And how this is possible?
Does it contain transmembrane domain?
You may not find a signal peptide in a membrane protein using computer programes.
