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Radioligand Assays and Non-specific Binding?

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#1 jummykorn



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Posted 16 February 2009 - 09:54 AM

Why is it important to define non specific binding with different drugs when first establishing a radioligand binding assay and why do most investigators choose to use a different compound from the one being investigated?

Does this have anything to do with dissociation constants?

any help would be appreciated!?

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