Tumor cells immortal?
Posted 25 March 2005 - 11:04 AM
Posted 29 March 2005 - 12:34 AM
they may be immortal. But only the cell culture will tell the truth...
For immortalized properties, cell should
be independent of growth factors to divide them
be independant of matrix attachment
have an hyperactive telomerase (if not they divide them until crisis where they are quite quiescent).
That are three basics properties of immortal cells.
But there are other cell lines that are immortal and must adhere little to plate for efficient division (such Hek 293 cells)
Posted 29 March 2005 - 10:07 PM
Posted 29 March 2005 - 10:11 PM
Posted 29 March 2005 - 11:54 PM
yep i made a mistake and would say that they can grow without having strong contacts with other cells, and at best, they can form clones (1 cell alone keep the power of dividing herself).
I'm sincerely sorry for that mistake...
Edited by fred_33, 29 March 2005 - 11:55 PM.