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Have any one know about Protein A


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#1 talent3003

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Posted 20 February 2005 - 12:54 AM

I want to know Which the specific region of Ig bind with protein A? and What Ig spp. can bind with protein A, e.g. cattle, rat, human, ruminant, mammal?

#2 ajames

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Posted 20 February 2005 - 10:45 PM

The Pierce website, a supplier of protein A, protein G and protein A/G has all of this kind of info http://www.piercenet...F7-B9787ED36581. It binds strongly to the Fc region of human and mouse IgG's although the binding to cow and sheep is weak and you may be better off with Protein G with these species.

#3 jadefalcon

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Posted 21 February 2005 - 07:07 AM

just for the sake of completeness:

the same info should be available from all the suplliers of protein A or G as for example roche:

http://www.roche-app...rt/1719394a.pdf

mike
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