Nuclear RNA knockdown with siRNA
Posted 09 February 2005 - 10:09 AM
I'm trying to knockdown the amount of a nuclear RNA. Does the Dicer-mediated degradation of the targeted RNA occur in the nucleus or in the cytoplasm??
If it occurs in the cytoplasm, does polyadenylated nuclear RNA get exported to the cytoplasm before it is localized to the nucleas??
Is knocking down a nuclear RNA feasible?
Thanks a lot,
Posted 10 February 2005 - 03:25 AM
Posted 18 November 2010 - 08:16 PM