I would like to know if addition of hydrogen peroxide to a growth medium reduces the oxygen content in the medium, leading to hypoxia or any sort of oxygen deficiency. Ldh (lactate dehydrogenase) transcription is induced during oxidative stress when I add H2O2 to my cell culture. From the literature I read, however, that LDH expression is induced during oxygen deficiency, which makes more sense to me. Can anyone explain to me whyLDH expression is induced during oxidative stress? Thanks
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