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Expression regulation by U1 snRNP though premature cleavage and polyadenylation

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#1 Jon Moulton

Jon Moulton


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Posted 10 June 2020 - 09:40 AM

"U1 telescripting is selectively required for full-length transcription of long genes, an unprecedented gene regulation mechanism based on gene length."

"Studies on U1 telescripting add to U1’s established role in splicing, placing it at the center of gene expression regulation, in both transcription and RNA processing."

U1 snRNP Telescripting Roles in Transcription and Its Mechanism.
Di C, So BR, Cai Z, Arai C, Duan J, Dreyfuss G.
Cold Spring Harb Symp Quant Biol. 2020 Jun 9:040451. doi:10.1101/sqb.2019.84.040451. Online ahead of print.



Jon D. Moulton
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