So I've been working on a research where we had a mice strain C57BL/6J fed on a high lipid died (western diet) And I've come across some strange findings which I wasn't able to find in other papers. I'm thinking it could be necrosis due to hyperlipidemia and the cytokine formations.
Picture 1: Light microscopy: Notice those dark circle shaped inclusions in the tubules:
Picture 2: Here's how they look up close using TEM microscopy.
If anyone could shed some light on what those could be, I'd be forever thankful.
Edited by Nina00, 16 August 2018 - 07:57 AM.