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Comparing efficacy of different anticoagulants

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#1 Daenerys



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Posted 13 January 2018 - 09:42 AM


I'm doing an experiment on different anticoagulants by comparing how they effect different specific clotting factors (measured via a factor activity assay). 

I have 2.5 mg of apixaban (in tablet form) and I wanted to make a stock solution out of it and then use 5 different final concentrations ranging from say 0 - 800 ng/ml i.e. 50ng/ml ... 150 ng/ml etc and use these solutions to spike normal plasma samples. Then I will perform the activity assays.

I have only have a limited supply of the anticoagulants in tablet forms and was wondering how I could make the final concentrations i.e. the stock then the exact concentrations I need

Any help is appreciated

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