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Can a siRNA derived from hairpin structure just like miRNA?

siRNA miRNA hairpin

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#1 Corey



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Posted 11 April 2017 - 06:04 AM

Hi everyone, nice to meet everybody in here, I got a simple question.

As far as I know, miRNA is derived from the long ssRNA sequence which can form a hairpin. And by introducing a specifically modified sequence which has 2 inverted tandem sequence flanking its both end, we can artificial create a hairpin which will then be processed by dicer and combine with AGO and form into a siRNA.

However, does organisms naturally possess any pathway or mechanism that can create siRNA via hairpin???


Thank you everyone for paying attention to my question.

Also tagged with one or more of these keywords: siRNA, miRNA, hairpin

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