Hi everyone, nice to meet everybody in here, I got a simple question.
As far as I know, miRNA is derived from the long ssRNA sequence which can form a hairpin. And by introducing a specifically modified sequence which has 2 inverted tandem sequence flanking its both end, we can artificial create a hairpin which will then be processed by dicer and combine with AGO and form into a siRNA.
However, does organisms naturally possess any pathway or mechanism that can create siRNA via hairpin???
Thank you everyone for paying attention to my question.