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Population genetics

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#1 Tina Hansen

Tina Hansen


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Posted 10 February 2017 - 07:29 AM

This may be general knowledge to genetics experts out there, but I have a question regarding how to estimate carrier probabilities.

Let's say the MAF at a given allele is 0.12 in a population in HWE. What is then the probability for an individual in that population of carrying that allele (on 1 or both chromosomes)? I am curious to know whether there are different ways of calculating this.

Thanks in advance,

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