when an extracellular ligand like epinephrine is transduced into the cell, one biochemical pathway ends in the nucleus.
this signal activates some transcription factors such as CREB which binds an specific nucleotic sequence in the DNA, this book (cell and molecular biology Gerald Karp p.633) says that " these trancription factors INCREASE THE RATE of initiation of transcription " i don´t understand it.
is it mean the transcription is always occuring? please help i love study cell biology is amazing