Jump to content

  • Log in with Facebook Log in with Twitter Log in with Windows Live Log In with Google      Sign In   
  • Create Account

Submit your paper to J Biol Methods today!
- - - - -

Migration of circular DNA vs circular/crosslinked peptide in gels

  • Please log in to reply
No replies to this topic

#1 labtastic



  • Active Members
  • PipPipPipPipPipPipPipPipPipPip
  • 141 posts

Posted 11 August 2015 - 12:54 PM

As I understand it:


1. Relaxed circular DNA migrates slower on a gel than linearized DNA (e.g. here)


2. Circular peptides (or intra-crosslinked peptides) run faster on a gel than linearized peptide


--> So circular DNA runs slower and circular peptides run faster than their linear counterparts.



Why the difference? 

Edited by labtastic, 11 August 2015 - 05:33 PM.

Home - About - Terms of Service - Privacy - Contact Us

©1999-2013 Protocol Online, All rights reserved.