As I understand it:
1. Relaxed circular DNA migrates slower on a gel than linearized DNA (e.g. here)
2. Circular peptides (or intra-crosslinked peptides) run faster on a gel than linearized peptide
--> So circular DNA runs slower and circular peptides run faster than their linear counterparts.
Why the difference?
Edited by labtastic, 11 August 2015 - 05:33 PM.