I am trying to measure IPSPs in a cell using current clamp. The cell does not have a stable membrane potential, but rather an oscillating membrane potential, because it is a pacemaker neuron. But the oscillation is not big, a few millivolts at most.
I am getting some results, but I just feel so uncertain because I can't use voltage clamp and control the membrane potential.
Has anyone done anything similar? Like measuring PSPs using current clamp?