I am in such a dilemma. I did a dose-response curve for some inhibitors in some cell lines and generated IC50s of the inhibitors.
I calculated the IC25 from the IC50 in other to combine with the IC50 of another inhibitor previously generated. The IC25s seem to inhibit about 50% of the cells now and the IC50 inhibits about 60-70%, Is there an explanations for this. Has anyone come across such a thing.... It is driving me nuts as I don't know how to explain the results.
Thanks for your help.