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Discovering protein僕ncRNA interactions from large-scale CLIP-Seq and RNA-Seq da

lncRNA GWAS CLIP-Seq RNA-Seq RBP

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#1 zhxq09

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Posted 15 January 2015 - 03:30 AM

Long non-coding RNAs (lncRNAs) are emerging as important regulatory molecules in developmental, physiological, and pathological processes. However, the precise mechanism and functions of most of lncRNAs remain largely unknown.

protein-lncRNA interaction resources:
RBP-lncRNA Base, that analyzing millions of RNA-binding protein (RBP) binding sites from 117 CLIP-Seq datasets generated by 50 independent studies, we identified 22,735 RBPlncRNA regulatory relationships.

RBP-lncRNA interactions were available at http://starbase.sysu...n/rbpLncRNA.php.

An invited paper described these proteinlncRNA interactions has been published in Frontiers journal.

The genomic context distributions of binding sites for 47 human RBPs.
fbioe-02-00088-g001.jpg

#2 CPRES

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Posted 15 January 2015 - 04:39 AM

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