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Gel filtration of COX-1 by aspirin


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#1 MCh

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Posted 03 January 2015 - 05:50 AM

Hello everyone! I was wondering what will be the elution products during the gel filtration of COX-1 when  use acetyl-3H apirin and aromatic ring-3H aspirin. How those two types of aspirin affect COX-1? Thank you in advance!



#2 MCh

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Posted 04 January 2015 - 06:43 AM

Is it right to think that since acetyl-3H aspirin inhibits/acetylates) cyclooxygenase (COX)-1, the elution product in this case will be arachidonic acid? If this is right, then what about aromatic ring-3H aspirin, i cant find anything helpful about this type….Any ideas will be helpful. Thank you in advance!






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