Jump to content

  • Log in with Facebook Log in with Twitter Log in with Windows Live Log In with Google      Sign In   
  • Create Account

Submit your paper to J Biol Methods today!
- - - - -

Is there always a presence of activated T cells in a healthy host?

  • Please log in to reply
1 reply to this topic

#1 Ahrenhase



  • Awaiting Authorisation
  • PipPipPipPipPipPipPipPipPipPip
  • 196 posts

Posted 18 December 2014 - 09:41 PM

I understand that after and immunogenic response, you get T cell activation (marked by CD69 and CD25 expression), and that activated T cell numbers contract after a while.  My question is that if you were to pull blood from a healthy individual  and not include CD25+ Tregs in your analysis, would you expect to see CD25+ or CD69+ activated T cells?

Edited by Ahrenhase, 18 December 2014 - 09:42 PM.

#2 bob1


    Thelymitra pulchella

  • Global Moderators
  • PipPipPipPipPipPipPipPipPipPip
  • 6,740 posts

Posted 19 December 2014 - 01:43 AM

Not being an immunologist, I may be completely wrong here:


My thoughts are - yes, you should. The body is constantly under assault by all sorts of antigens (e.g. in the gut and nasal passages), so there should be a small population of activated T cells all the time.

Home - About - Terms of Service - Privacy - Contact Us

©1999-2013 Protocol Online, All rights reserved.