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IgG/IgM levels in infections/Brucellosis

Brucellosis antibodies IgG IgM Infection

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#1 ethanjvn

ethanjvn

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Posted 09 November 2014 - 11:44 PM

I have an urgent question for which I have been given a deadline. So please help!

In the acute stage of Brucellosis there is an initial production of IgM antibodies, followed closely by production of IgG antibodies(in the chronic stage). IgG-class antibodies may decline after treatment( so the active phase of the disease is literally over); however, high levels of circulating IgM-class antibodies may be found without any active disease( and gradually decrease over a period of time after the end of the disease ).

Having said all that, I've been told that for other infections ( maybe not all of them ) the story is the other way round. I mean it's the IgM that drops by the end of the active phase of the disease (treatment). And IgG stays for quite some time after the disease.

Now this is the question I've been asked:what's the reason for this difference?

BTW I tried to draw the charts the prof. showed us in the attachment. Sorry if it's not so good.

Please... Help.
THANKS

Attached Thumbnails

  • Screenshot_2014-11-10-11-04-16-1.png
  • Screenshot_2014-11-10-11-09-52-1.png

Edited by ethanjvn, 09 November 2014 - 11:50 PM.






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