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Intracerebral microdialysis


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#1 Cornelius

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Posted 09 July 2004 - 06:02 PM

Dear colleagues, I am interested in using microdialysis techniques to investigate the effects of some interventions in brain, but I am a beginner in this kind of technique. I would like to know:

What neurotransmitters can microdialysis extract?
Can proteins such as growth factors be extracted through microdialysis?

Many thanks!! :)

#2 Sergey

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Posted 23 August 2004 - 12:36 PM

Low molecular substances (under 1000 Da) goes without any limitations.
Peptides and proteins are on the same manner, but in this case membrane chracteristis play role. Different membrans - different molecular masses are possible. Growth factors are often big molecules and many of them do not pass. Learn about your membrane/probe parameters.




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