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Fatty Acid Synthesis


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#1 caters

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Posted 28 July 2014 - 02:39 PM

I looked up fatty acid synthesis and it says that for saturated fatty acid formation that 6 steps happen with 2 carbon acetyl CoA molecules until palmatic acid which is a 16 carbon fatty acid is formed.

 

Fatty acids are just carboxylic acids which naturally occur with 4 or more carbons but can have less than 4 carbons. How would all those other fatty acids by length be synthesized because surely 16C fatty acids are not the only ones synthesized.


Edited by caters, 28 July 2014 - 03:13 PM.


#2 phage434

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Posted 29 July 2014 - 05:31 AM

The synthesis, as you have read, is a cyclic process where the length is increased by two carbons every cycle. If the cycle stops early or goes on, either longer or shorter fatty acid chains are formed.



#3 caters

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Posted 29 July 2014 - 07:24 AM

yeah but I have only read that palmitic acid which is a 16 carbon, straight chain, saturated fatty acid is what is formed during fatty acid synthesis.

 

Could it be that palmitic acid is the major product but other fatty acids form as well?



#4 phage434

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Posted 29 July 2014 - 05:01 PM

Yes, and of course there are also modifications which produce unsaturated versions of these fatty acids.



#5 caters

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Posted 29 July 2014 - 07:48 PM

and modifications for branched chain fatty acids. But then how do the odd numbered ones get formed like a 33C fatty acid for example if 2 carbons are added per cycle?



#6 Tabaluga

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Posted 30 July 2014 - 03:52 AM

Via Propionyl-CoA. You can find a lot of infos by googling odd number fatty acid synthesis, e.g. this one: http://www.cliffsnot...hed-fatty-acids

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