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Mouse Breeding Flox Cre

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#1 hutcherson



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Posted 02 May 2014 - 09:30 AM



Currently we have a fl/fl, apoe -/- mouse wanting to mate it to a cre/+, apoe -\- mouse. 


Will the offspring be    50:50               fl/+, Cre/+, apoe-/- or fl/+, ++, apoe -\-?   


Next step      fl/+, Cre/+, apoe-/-   X   fl/+, Cre/+, apoe-/-


Could someone give me the breakdown of genotypes and percentages?  Punnett square? 

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