I am trying to extract Dna from fungus (Alternaria alternata). I need really high quality dna for southern blots. Till now, i have tried a variety of methods, from CTAB method to qiagen kits. But, all i get is degraded dna or very low concentrations that are not usable at all. I always get a nice pellet but when i run the dna on a gel, it shows up as a smear.