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Apo Transferrin vs Human transferrin

culture media cell culture reagant keratinocytes

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#1 roxx_gurl

roxx_gurl

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Posted 15 November 2013 - 03:54 AM

Greetings,

 

What is the difference between apo-transferrin and human transferrin? I got their definition of apo-transferrin is free from iron binding while transferrin based on Sigma product is already half-saturated with iron. Once saturated with iron, i.e forming holo-transferrin it will bring iron into cell by receptor binding of the cell. I am confused why Sigma need to have two different products which in the end both will be saturated with iron and help with cell metabolism and which product is good for cell culture like keratinocytes, Can somebody help me. Thanks







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