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Finding functions for genes in long gene lists


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#1 K-dude

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Posted 12 September 2013 - 06:42 AM

Hi!

Is there a way of getting a short summary of gene functions without having to search for each individual gene?

I.e., can I paste my gene list somewhere, hit enter and get a back list of gene functions?

Thanks

 



#2 PhalanxBio

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Posted 12 September 2013 - 07:44 AM

There are a number of tools that allow you to do this.  Ingenuity Pathway Analysis is a very powerful tool, but you'll need a subscription:

 

http://www.ingenuity.com/products/ipa

 

Some free online tools include:

 

DAVID Bioinformatics http://david.abcc.ncifcrf.gov/

 

Panther;http://www.pantherdb.org/genes/

 

There are definitely others.  I highly recommend DAVID - very easy and it will give you the results you are looking for!



#3 Tabaluga

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Posted 13 September 2013 - 09:10 AM

I have a question on that issue. Let's say I have a list and determine by said databases that most of the genes are involved in cell cycle regulation/proliferation/mitosis. How can I find out whether they are positive or negative reulators of the cell cycle ? Do I have to look up every single gene or is there also a way to determine this for a whole list of genes ?


Il dort. Quoique le sort fût pour lui bien étrange,
Il vivait. Il mourut quand il n'eut plus son ange;
La chose simplement d'elle-même arriva,
Comme la nuit se fait lorsque le jour s'en va.

 





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