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What is the reason of doing proteomics work?


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#1 chandch

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Posted 04 August 2013 - 03:02 PM

Hello all,

 

As a newbie, I am interested to know the rationale of doing proteomics work. As many of us know that "proteome analysis is required to determine which proteins have been conditionally expressed, how strongly, and whether any posttranslational modifications are affected". (between health and diseased tissue i.e., human or plant tissue)

 

What is the next step, If I know a protein that is expressed in response to biotic and abiotic factors? Is it only useful for writing a papers? or How can this results be useful?

 

 

Thank you



#2 newborn

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Posted 07 August 2013 - 05:28 AM

It can be an ideal target for treatment of diseases, it can lead to another important mechanism of something.

It can also be a biomarker for some serious disease.



#3 hobglobin

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Posted 07 August 2013 - 08:03 AM

here is a nice review: http://mmbr.asm.org/...nt/66/1/39.full
You can read only the chapter(s) dealing with your questions, which is in the Introduction mainly.
Anyway surely there are as with all other methods challenges and limitations, making it e.g. difficult to interpret results or finding useful applications.

Therefore also in proteomics some research is surely "just" pure research, even if it is said what wonderful applications can come out of this. But also pure research is good and necessary.


One must presume that long and short arguments contribute to the same end. - Epicurus
...except casandra's that belong to the funniest, most interesting and imaginative (or over-imaginative?) ones, I suppose.

That is....if she posts at all.





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