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Drugs that cause DNA double strand breaks

DNA double strand breaks Drugs DNA damage Cell Culture Agents

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#1 Epigeneticist

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Posted 23 July 2013 - 08:34 PM

I am looking for drugs/agents that cause DNA double strand breaks. I would like to use them in cell culture. Etoposide and Doxorubicin, are these good or are there better drugs? Typical treatment is 4-8hrs or 12-2hrs?

Thanks!

#2 bob1

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Posted 24 July 2013 - 01:15 AM

I have used Dox, it works well, but is very toxic, I would say go for the shorter time points.





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