Difference between wild-type lentivirus and integrase-deficient lentivirus
Posted 18 June 2013 - 01:07 AM
I don't know what is the difference between wild-type lentivirus and integrase-deficient lentivirus.
Are they used in different purpose? If so, what is it?
Thanks in advance.
Posted 18 June 2013 - 01:23 AM
Posted 18 June 2013 - 06:30 AM
Do you mean integrase-deficient lentivirus (IDLV) doesn't integrate into host genome?
But some people used IDLV to capture virus-preferential integration site (PMID: 21822255).
It means that IDLV also integrate into host genome.
Because of this, I don't know the difference between two viruses/viral vector.
If you know something more, please let me know.