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Protein sequence conservation

Protein sequence

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#1 j47027

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Posted 07 June 2013 - 12:48 PM

What is generally regarded as highly conserved protein sequence?..Percentage wise

I was looking at of the same proteins form different species and the alignment score comes in at 76%.
560AA residue proteins

#2 labtastic

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Posted 08 June 2013 - 12:30 PM

I think it depends on what species you are comparing. If these proteins are 76% identical between humans, e coli, frog and some archaea, then yes, that is a highly conserved protein. If the comparisons are between humans, chimps and orangutans, then that's probably a relatively divergent protein. In general though, yes, 76% conserved is a pretty well conserved protein.

#3 j47027

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Posted 10 June 2013 - 02:34 PM

Thanks, I had a presentation to give and I need the answer incase I was asked that question!




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