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"Dear" GPCR


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#1 Tom M

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Posted 20 May 2013 - 08:08 AM

A colleague of mine determined through a genomic array that diseased renal tissue expressed 100x more DNA than non-diseased renal tissue for a G protein coupled receptor that was identified as the dual endothelin 1/angiotensin II receptor (DEAR).  Does anyone know anything about this receptor or can suggest a publication or two that discuss it?  Thanks.

Tom

#2 pcrman

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Posted 21 May 2013 - 11:12 PM

Do you mean 100x more RNA expression? What is genomic array?

#3 Tom M

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Posted 22 May 2013 - 01:11 PM

View Postpcrman, on 21 May 2013 - 11:12 PM, said:

Do you mean 100x more RNA expression? What is genomic array?

yes, 100x greater mRNA expression.




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