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proteomics, SILAC, outlier detection

SILAC proteomics outlier

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#1 gorlukatko

gorlukatko

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Posted 03 May 2013 - 04:04 AM

Hi,
We started to do SILACs recently. I would like to analyze the resulting low/heavy ratio lists by some better method than just a simple FC. Is there some (free) software that implements some statistical methods for detection of proteins with changed low/heavy ratio? What is a proper handling of datasets where you have low/heavy and heavy/low replicates.
thank you
john





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