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Stimulate receptor constitutive activity

muscarinic receptors CHO constitutive activity

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#1 Annasae

Annasae

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Posted 16 April 2013 - 04:24 AM

Hello, I am working with CHO cells expressing the hM2 receptor. It happens that in some experiment the receptors are inactive and in others the show spontaneous activity, with no apparent reason. Now, I would like my receptor to be always constitutively active, for example using a certain type of buffer. Did anyone ever achieved this in his experiments? I don't find any reference..





Also tagged with one or more of these keywords: muscarinic receptors, CHO, constitutive activity

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