So im looking at the changes in drug resistance of an ovarian cancer cell line when exposed to two different populations of exosomes (and a control without exosomes), and different concentrations of cisplatin. From this I will create a kill curve, but I want to use a statistical method to analyse and compare all three curves as a whole, rather than just comparing different points on each curves. Is there way to do this?!
I hope this makes sense!
Submit your paper to J Biol Methods today!
How to choose what statistical analysis to use....
1 reply to this topic
Posted 10 March 2013 - 11:21 AM
Fit the ‘kill curves’ to a 4 parameter Hill equation, for which there are a number of past discussions on this forum. Chances are that the only parameter that varies is the IC50 which you can then use compare between your three curves.