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How to choose what statistical analysis to use....


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#1 ekey4898

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Posted 08 March 2013 - 02:42 PM

Hey!
So im looking at the changes in drug resistance of an ovarian cancer cell line when exposed to two different populations of exosomes (and a control without exosomes), and different concentrations of cisplatin. From this I will create a kill curve, but I want to use a statistical method to analyse and compare all three curves as a whole, rather than just comparing different points on each curves. Is there way to do this?!
I hope this makes sense!
Thanks

#2 DRT

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Posted 10 March 2013 - 11:21 AM

Fit the ‘kill curves’ to a 4 parameter Hill equation, for which there are a number of past discussions on this forum. Chances are that the only parameter that varies is the IC50 which you can then use compare between your three curves.




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