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Help clarify mucoid and non-mucoid Pseudomonas aeruginosa

Pseudomonas aeruginosa mucoid non-mucoid biofilm CF

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#1 tihong10

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Posted 01 February 2013 - 06:58 AM

Hi,

I came across the term mucoid and non-mucoid when reading articles about Pseudomonas aeruginosa (PA) biofilms in Cystic Fibrosis patients, and I couldn't find any explanation about what those terms meant exactly. Is mucoid another word for PA growing as a biofilm and non-mucoid for planktonic PA?

If anyone has knowledge in this area please help me understand the difference.

Thank You!

#2 Tabaluga

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Posted 01 February 2013 - 07:46 AM

I think non-mucoid Pseudomonas can also produce biofilms, if I'm not mistaken....
This website http://textbookofbac...seudomonas.html says:

"P. aeruginosa isolates may produce three colony types. Natural isolates from soil or water typically produce a small, rough colony. Clinical samples, in general, yield one or another of two smooth colony types. One type has a fried-egg appearance which is large, smooth, with flat edges and an elevated appearance. Another type, frequently obtained from respiratory and urinary tract secretions, has a mucoid appearance, which is attributed to the production of alginate slime. The smooth and mucoid colonies are presumed to play a role in colonization and virulence."

As for planktonic PA, I don't know how it's defined in relation to mucoid/non-mucoid, unfortunately...

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#3 pito

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Posted 01 February 2013 - 11:27 AM

Check this: http://ajcp.ascpjour...8/1/32.full.pdf

Read the paper (its short) and check the references, it will be more clear to you then.
It has indeed nothing to do with the possibility to form a biofilm.
ANd check this: http://www.answers.com/topic/bacteria

Mucoid is thus pretty literal (mucus, slime layer around the bacteria..)

If you don't know it, then ask it! Better to ask and look foolish to some than not ask and stay stupid.


#4 tihong10

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Posted 05 February 2013 - 09:47 AM

Thanks for the interesting looking article!





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