Hi
I am trying to test HCV protease inhibitor on NS3 protein expressed in adenovirus vector. I discovered lately that adenovirus has AVP(cysteine protease) which has charcters similar to NS3 protease, do you think this will interfere with my results?
0
1 reply to this topic
#2
bob1
-
- Global Moderators
-
- 4,427 posts
Thelymitra pulchella
234
Excellent
Excellent
Posted 23 January 2013 - 12:42 AM
Depending on the variant of Ad you use, the cys-protease may have been deleted. You could try expressing the NS3 off a plasmid?
