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protein-protein interaction


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4 replies to this topic

#1 zogene

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Posted 20 January 2013 - 03:24 PM

Hello

Can anybody tell me and explain to me how a protein interacts with other one, I mean chemically, and if there is any text book or literature explains that I will be grateful if it is provided? I have been searching for along time for that with no result.

many thanks and regards
zogene

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#2 Tabaluga

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Posted 20 January 2013 - 03:43 PM

Protein-protein interactions are in most cases non-covalent bonds (i.e. van der Waals forces, hydrogen bonds, ionic bonds).

This script might cover what you're looking for:
http://www.cellbio.d...socALL(2-5).pdf

Also see this http://casegroup.rut...0_protein2b.pdf
and this http://webhost.bridg...noncovalent.htm

Edited by Tabaluga, 20 January 2013 - 03:44 PM.

Il dort. Quoique le sort fût pour lui bien étrange,
Il vivait. Il mourut quand il n'eut plus son ange;
La chose simplement d'elle-même arriva,
Comme la nuit se fait lorsque le jour s'en va.

 


#3 zogene

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Posted 23 January 2013 - 05:44 PM

Hello

Thank you so much for response, actually what I am looking for is more details about the interaction that happens between two different proteins like a membarne protein with its ligand coactivator or corepresso,r what is the type of interaction happens between them, is it right to say that protein interacts as a heterodimer or a homodimer?
really it is hard for me to categorize them, can you?

many thanks for reponse

"Be the change that you wish to see in the world"


#4 Tabaluga

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Posted 25 January 2013 - 06:24 AM

I'm sorry, I'm not quite sure I understand your question. Do you have an example or something ?

Il dort. Quoique le sort fût pour lui bien étrange,
Il vivait. Il mourut quand il n'eut plus son ange;
La chose simplement d'elle-même arriva,
Comme la nuit se fait lorsque le jour s'en va.

 


#5 zogene

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Posted 30 January 2013 - 02:28 PM

Hello
thank you so much for help I found what I was lloking for many thanks for responses.
regards

"Be the change that you wish to see in the world"





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