4 replies to this topic

[zogene]

Hello

Can anybody tell me and explain to me how a protein interacts with other one, I mean chemically, and if there is any text book or literature explains that I will be grateful if it is provided? I have been searching for along time for that with no result.

many thanks and regards
zogene

[Tabaluga]

Protein-protein interactions are in most cases non-covalent bonds (i.e. van der Waals forces, hydrogen bonds, ionic bonds).

This script might cover what you're looking for:
http://www.cellbio.d...socALL(2-5).pdf

Also see this http://casegroup.rut...0_protein2b.pdf
and this   http://webhost.bridg...noncovalent.htm

Edited by Tabaluga, 20 January 2013 - 03:44 PM.

[zogene]

Hello

Thank you so much for response, actually what I am looking for is more details about the interaction that happens between two different proteins like a membarne protein with its ligand coactivator or corepresso,r what is the type of interaction happens between them, is it right to say that protein interacts as a heterodimer or a homodimer?
really it is hard for me to categorize them, can you?

many thanks for reponse

[Tabaluga]

I'm sorry, I'm not quite sure I understand your question. Do you have an example or something ?

[zogene]

Hello
thank you so much for help I found what I was lloking for many thanks for responses.
regards