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Apoptosis inducing siRNA?

apoptosis siRNA cell culture

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#1 mekelseyb

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Posted 16 January 2013 - 11:02 AM

I am looking for a target gene, that when knocked down by siRNA will cause apoptosis. I have searched the literature and have yet to find anything that might be helpful.

I did find a apoptosis inducing siRNA produced by Altogene. They claim it will cause apoptosis in all cell lines. Any idea what their target might be?

Thanks!

#2 bob1

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Posted 16 January 2013 - 12:19 PM

You could try MDM2 KD. MDM2 is the negative regulator of p53, high levels of p53 should induce apoptosis.





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